If they are to claim their first win since early May, they will have to do it without left back Ashley Cole, who picked up a red card against the San Jose Earthquakes in last week's Cali Clasico.
Nonetheless, the Galaxy should be boosted by the returns of Gyasi Zardes and Robbie Keane after the forward duo missed all of last month's games through international duty.
The Whitecaps, meanwhile, arrive to this game on the back of a heartbreaking defeat to Toronto FC in the Canadian Championship final. That said, Carl Robinson's side are unbeaten in their last three games against the Galaxy, including a 1-0 victory at StubHub center last season.
As such, with the Galaxy reaching the halfway point of the season, victories are becoming more important with every passing week. The hope now for the Galaxy is that fans will be celebrating more than Independence Day at the end of the night.
Match date/time: Monday 10:30 pm EST, 7:30pm local
Venue: StubHub Center, Carson, California
TV: Time Warner Cable SportsNet, Time Warner Cable Deportes (Spanish)
Streaming: MLS Live (local blackout)