In wake of Nigel de Jong's three-game ban for his tackle on Darlington Nagbe, the Galaxy arrive to The Lone Star State short on midfielders and with several players returning from injury.
Of course, from the start, Bruce Arena should have expected to be without the Dutch midfielder for at least this game, and in turn, Steven Gerrard could be rushed to the starting lineup fold after just resuming normal training last week.
To add to De Jong's suspension is the absence of Robbie Rogers, who left last weekend's match with a small hip injury. Bruce Arena, though, should be boosted by the returns of Dan Kennedy and A.J. DeLaGarza to the first team squad.
In total, the Galaxy are winless in their last four visits to Houston. Owen Coyle's side is the highest scoring team in the league and they narrowly drew with the Seattle Sounders last weekend thanks to a stoppage time goal.
The Galaxy will have to prove their mettle on the road if they want to escape Texas with a win.
Match date/time: Friday 7:00pm EST, 6:00pm local
Venue: BBVA Compass Stadium, Houston, Texas
TV: Unimas (Spanish)
Streaming: MLS Live (local blackout)